1型（胰岛素依赖型）糖尿病的易感性由MHCⅡ类分子决定。那DR4呢？ - Suppr

Suppr

超能文献

Susceptibility to type 1 (insulin-dependent) diabetes mellitus is determined by MHC class II molecules. What about DR4?

作者信息

Mijovic C H, Jenkins D, Penny M A

机构信息

Department of Medicine, University of Birmingham, UK.

出版信息

Diabetologia. 1993 Nov;36(11):1210-1. doi: 10.1007/BF00401069.

DOI:10.1007/BF00401069

PMID:8270139

Abstract

摘要

相似文献

Susceptibility to type 1 (insulin-dependent) diabetes mellitus is determined by MHC class II molecules. What about DR4?

Diabetologia. 1993 Nov;36(11):1210-1. doi: 10.1007/BF00401069.

Class I HLA is associated with age-at-onset of IDDM, while class II HLA confers susceptibility to IDDM.

Diabetologia. 1995 Dec;38(12):1493-5. doi: 10.1007/BF00400620.

Type 1 diabetes in the Spanish population: additional factors to class II HLA-DR3 and -DR4.

BMC Genomics. 2005 Apr 20;6:56. doi: 10.1186/1471-2164-6-56.

In Finland insulin gene region encoded susceptibility to IDDM exerts maximum effect when there is low HLA-DR associated risk. DiMe (Childhood Diabetes in Finland) Study Group.

Diabetologia. 1995 Oct;38(10):1223-9. doi: 10.1007/BF00422373.

Genetic susceptibility linked to DR4 haplotypes in diabetes of type-1a or associated with polyendocrinopathies (type-1b). The Diabetes Study Group from West France.

Tissue Antigens. 1991 Oct;38(4):183-5. doi: 10.1111/j.1399-0039.1991.tb01894.x.

HLA-associated susceptibility to type 2 (non-insulin-dependent) diabetes mellitus: the Wadena City Health Study.

Diabetologia. 1993 Mar;36(3):234-8. doi: 10.1007/BF00399956.

Molecular aspects of HLA class II and some autoimmune diseases.

Eur J Immunogenet. 1993 Jun;20(3):153-64. doi: 10.1111/j.1744-313x.1993.tb00106.x.

Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects.

Diabetologia. 1992 May;35(5):419-24. doi: 10.1007/BF02342437.

Possible human leukocyte antigen-mediated genetic interaction between type 1 and type 2 Diabetes.

J Clin Endocrinol Metab. 2001 Feb;86(2):574-82. doi: 10.1210/jcem.86.2.7170.

Does the locus on chromosome 11 implicated in susceptibility to HLA-DR4 dependent type I diabetes mellitus also affect susceptibility to rheumatoid arthritis?

Ann Rheum Dis. 1992 Nov;51(11):1250-1. doi: 10.1136/ard.51.11.1250.

引用本文的文献

Genetic predisposition to IDDM.

Clin Rev Allergy Immunol. 2000 Dec;19(3):227-46. doi: 10.1385/CRIAI:19:3:227.

Relationships among 64k autoantibodies, pancreatic beta-cell function, HLA-DR antigens and HLA-DQ genes in patients with insulin-dependent diabetes mellitus in Korea.

Korean J Intern Med. 1995 Jan;10(1):1-9. doi: 10.3904/kjim.1995.10.1.1.

本文引用的文献

HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation.

J Immunol. 1993 Mar 15;150(6):2263-72.

Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus.

Diabetologia. 1993 May;36(5):371-7. doi: 10.1007/BF00402270.

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes.

Diabetes. 1987 Jan;36(1):114-7. doi: 10.2337/diab.36.1.114.

Association of HLA-DQw3 (TA10-) with type I diabetes occurs with DR3/4 but not DR1/4 patients.

Diabetes. 1988 Jul;37(7):926-9. doi: 10.2337/diab.37.7.926.

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles.

J Clin Invest. 1989 Mar;83(3):830-5. doi: 10.1172/JCI113965.

HLA-DQ beta sequence polymorphism and genetic susceptibility to IDDM.

Diabetes. 1990 Jan;39(1):96-103. doi: 10.2337/diacare.39.1.96.

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A beta-chain or normal I-E alpha-chain.

Nature. 1990 Jun 21;345(6277):727-9. doi: 10.1038/345727a0.

Genetics of diabetes. Trans-racial gene mapping studies.

Baillieres Clin Endocrinol Metab. 1991 Jun;5(2):321-40. doi: 10.1016/s0950-351x(05)80130-2.

DRB genotyping supports recessive inheritance of DR3-associated susceptibility to insulin-dependent diabetes mellitus.

Am J Hum Genet. 1991 Jul;49(1):49-53.

Susceptibility to IDDM in a Chinese population. Role of HLA class II alleles.

Diabetes. 1992 Aug;41(8):914-9. doi: 10.2337/diab.41.8.914.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验