McDermott F T, Roudnew B
Virchows Arch B Cell Pathol. 1976 Dec 2;22(4):353-7. doi: 10.1007/BF02889229.
Colonic crypt cell population kinetics were investigated by autoradiography with tritiated thymidine in rats 60 days after resection of a jejunal segment equivalent to 40% of the length of the small intestine. Controls were subjected to transection and anastomosis. The mean total number of cells and the mean number of labelled cells per crypt cell column were estimated. The distribution of the proliferative and mature cell zones was obtained by determing the percentage of labelled cells at each cell position in the crypt cell columns. The mean total number of cells, mean number of labelled cells per crypt cell column and sizes of the proliferative and mature cell zones were unchanged (P less than 0.1). It is concluded that 40% small intestine resection does not influence the cell population kinetics of the colonic crypts of Lieberkühn.
在切除相当于小肠长度40%的空肠段60天后，用氚标记的胸腺嘧啶核苷通过放射自显影术研究大鼠结肠隐窝细胞群体动力学。对照组进行横断和吻合术。估计每个隐窝细胞柱的平均细胞总数和平均标记细胞数。通过确定隐窝细胞柱中每个细胞位置的标记细胞百分比，得出增殖细胞区和成熟细胞区的分布。平均细胞总数、每个隐窝细胞柱的平均标记细胞数以及增殖细胞区和成熟细胞区的大小均未改变（P<0.1）。结论是，40%小肠切除不影响利伯kühn结肠隐窝的细胞群体动力学。
