Van Haesendonck E, Missotten L
Eye Research Laboratory, Katholieke Universiteit Leuven, U.Z. Sint-Rafaël, Belgium.
Neurosci Lett. 1993 Oct 29;161(2):187-90. doi: 10.1016/0304-3940(93)90290-2.
The distribution of GABA in the perifoveal and the near and far peripheral region of human retina was studied with peroxidase anti-peroxidase immunocytochemistry applied on semithin epoxy resin sections. Among the labeled amacrine cells in these regions, four types can be identified: putative diffuse A2 amacrines, stratified semilunar amacrines, interstitial amacrines and small displaced amacrines. GABA-immunoreactive interplexiform cells and ganglion cells also occur. Contrary to previous post-embedding studies, our preparations show that some bipolar cells in the near and far peripheral region are GABA-immunopositive. This indicates that a number of bipolar cells in human retina does have an enhanced GABA content.
应用过氧化物酶抗过氧化物酶免疫细胞化学方法,在半薄环氧树脂切片上研究了GABA在人视网膜中央凹周围以及近、远周边区域的分布。在这些区域标记的无长突细胞中,可识别出四种类型:假定的弥散型A2无长突细胞、分层半月形无长突细胞、间隙性无长突细胞和小移位无长突细胞。也存在GABA免疫反应性双极细胞和神经节细胞。与先前的包埋后研究相反,我们的标本显示,近周边和远周边区域的一些双极细胞是GABA免疫阳性的。这表明人视网膜中的一些双极细胞确实具有增加的GABA含量。