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[双等位基因遗传标记与亲属关系的判定]

[Bi-allelic genetic markers and the determination of family relationships].

作者信息

Salmon D, Brocteur J

出版信息

C R Acad Hebd Seances Acad Sci D. 1976 Nov 29;283(14):1609-11.

PMID:827371
Abstract

A very useful index for the validation of family relationship by means of genetic markers is the proportion of males in the population whose phenotype makes paternity of a child of known phenotype impossible: the proportion often indicates probability of exclusion of paternity. It may be proved in the case of biallelic mendelian systems that this probility of exclusion of paternity may be modified by close relationship between the mother and father of the child or between the real father of the child and the presumptive father.

摘要

通过遗传标记来验证亲子关系的一个非常有用的指标是,在人群中其表型使得不可能成为已知表型孩子生父的男性比例:这个比例常常表明排除父权的概率。在双等位基因孟德尔系统的情况下可以证明,这种排除父权的概率可能会因孩子的母亲和父亲之间、孩子的实际父亲和推定父亲之间的近亲关系而改变。

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