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Synthesis and characterization of a penicillin-poly(L-lysine) which recognizes human IgE anti-penicillin antibodies.

作者信息

Caneva E, Di Gennaro P, Farina F, Orlandi M, Rindone B, Falagiani P

机构信息

Dipartimento di Chimica Organica e Industriale, Università di Milano, Italy.

出版信息

Bioconjug Chem. 1993 Sep-Oct;4(5):309-13. doi: 10.1021/bc00023a001.

DOI:10.1021/bc00023a001
PMID:8274512
Abstract

Conjugates of poly(L-lysine) containing a penicillin or a penicilloyl residue were prepared and characterized by 1H NMR and by size-exclusion HPLC. These conjugates and conjugates with human serum albumin were used in radioallergosorbent tests (RAST) for the determination of allergy toward penicillins.

摘要

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Determination of IgE antibodies to the benzylpenicilloyl determinant: a comparison of the sensitivity and specificity of three radio allergo sorbent test methods.针对青霉素酰基决定簇的IgE抗体的测定:三种放射变应原吸附试验方法的敏感性和特异性比较。
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