Sheen-Chen S M, Chou F F
Department of Surgery, Chang-Gung Memorial Hospital at Kaohsiung, Taiwan, R.O.C.
Eur J Surg. 1993 Sep;159(9):457-9.
To compare the effects of a conventional cold scalpel and electrocautery in modified radical mastectomy.
A non-randomised controlled trial.
Teaching hospital in Southern Taiwan.
101 consecutive patients with primary breast cancer who underwent modified radical mastectomy between July 1987 and June 1989.
The 44 patients during the first year were allocated to have skin flaps fashioned conventionally with a cold scalpel and the 57 patients during the second year, by electrocautery.
Morbidity and mortality among the 101 patients who underwent modified radical mastectomy.
The groups were comparable in regard to age, menopause, cancer stage, weight of specimen and histological type of cancer. The mean blood loss was 567 ml when scalpel was used and 150 ml when electrocautery was used (p < 0.001). The postoperative fall in packed cell volume was significantly greater in the scalpel group (0.75 [0.26] compared with 0.28 [0.15], p < 0.001) and more patients in this group required transfusion (9 compared with 0, p < 0.01). There were no deaths in either group. There were no significant differences in operation time, total post-operative Hemovac drainage, postoperative hospital stay, the number of lymph nodes removed, the number of metastatic lymph nodes, and postoperative complications between the groups.
Electrocautery is a safe, convenient and rational method for constructing skin flaps in modified radical mastectomy, and patients do not need blood transfusions.
比较传统冷刀与电灼术在改良根治性乳房切除术中的效果。
非随机对照试验。
台湾南部的教学医院。
1987年7月至1989年6月期间连续101例行改良根治性乳房切除术的原发性乳腺癌患者。
第一年的44例患者采用传统冷刀制作皮瓣,第二年的57例患者采用电灼术制作皮瓣。
101例行改良根治性乳房切除术患者的发病率和死亡率。
两组在年龄、绝经状态、癌症分期、标本重量和癌症组织学类型方面具有可比性。使用手术刀时平均失血量为567ml,使用电灼术时为150ml(p<0.001)。手术刀组术后红细胞压积下降明显更大(分别为0.75[0.26]和0.28[0.15],p<0.001),该组更多患者需要输血(分别为9例和0例,p<0.01)。两组均无死亡病例。两组在手术时间、术后总负压引流、术后住院时间、切除淋巴结数量、转移淋巴结数量和术后并发症方面无显著差异。
电灼术是改良根治性乳房切除术中制作皮瓣的一种安全、方便且合理的方法,患者无需输血。