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[上丘电刺激对大脑皮质局灶性癫痫活动的影响]

[The effect of the electrical stimulation of the superior colliculli on focal epileptic activity in the cerebral cortex ].

作者信息

Kryzhanovskiĭ G N, Shandra A A, Godlevskiĭ L S, Vikhrestiuk S L

出版信息

Biull Eksp Biol Med. 1993 Aug;116(8):119-22.

PMID:8274674
Abstract

Acute experiments in rats showed that SC electrical stimulation (ES) (100 Hz, 5 V, 0.25 ms) resulted in suppression of the epileptic activity in contralateral strychnine-induced (0.1%; 1.0%) focus and shortening of the focus existence time. After electrocoagulation of SC ES-zone the EpA in the focus was restored. ES of SC ipsilateral to strychnine-induced (0.1%) focus caused an increase in the spike frequencies but significant part of the antiepileptic system.

摘要

对大鼠进行的急性实验表明,脊髓电刺激(ES)(100赫兹、5伏、0.25毫秒)可抑制对侧士的宁诱导(0.1%;1.0%)病灶的癫痫活动,并缩短病灶存在时间。在对脊髓电刺激区域进行电凝后,病灶中的癫痫发作活动恢复。对士的宁诱导(0.1%)病灶同侧的脊髓进行电刺激会导致棘波频率增加,但这是抗癫痫系统的重要组成部分。

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