Godlevskiĭ L S, Shandra A A
Biull Eksp Biol Med. 1983 Apr;95(4):23-5.
Acute experiments on cats were made with the use of an experimental multifocal epileptic complex (MEC) which was created by local application of different concentrations of penicillin to different zones of the neocortex. At the early stages of the MEC the epileptic activity in the seizure foci increased during electrical stimulation (ES, 100-300 Hz) of the contralateral dentate nucleus. As the epileptic activity of the MEC descended up to the disappearance of some of the dependent foci, ES elicited the suppression of the epileptic discharges in the remaining foci. ES of the dentate nucleus did not affect the overall duration of MEC existence. It is inferred that the dentate nucleus belongs to the antiepileptic system of the brain.
利用实验性多灶性癫痫复合体（MEC）对猫进行急性实验，该复合体是通过将不同浓度的青霉素局部应用于新皮质的不同区域而创建的。在MEC的早期阶段，对侧齿状核的电刺激（ES，100 - 300 Hz）会使癫痫病灶中的癫痫活动增加。随着MEC的癫痫活动下降直至一些从属病灶消失，电刺激会使其余病灶中的癫痫放电受到抑制。齿状核的电刺激并不影响MEC存在的总时长。据推测，齿状核属于大脑的抗癫痫系统。
