Nicolini H, Weissbecker K, Mejía J M, Sánchez de Carmona M
Unidad de Genética Molecular Psiquiátrica PUIS-UNAM, Instituto Mexicano de Psiquiatría, D.F.
Arch Med Res. 1993 Summer;24(2):193-8.
Twenty seven obsessive-compulsive disorder (OCD) patients were studied at the Instituto Mexicano de Psiquiatría in Mexico City. This is the first sample of OCD patients studied in Latin America. There was a significant sex ratio difference and a significant difference in the type of obsessions and compulsions displayed by males and females. Co-morbidity data demonstrated a high frequency of obsessive-compulsive personality disorders, depression, sexual abuse, suicidal attempts and neurological damage. Approximately one third of OCD cases demonstrated a positive family history. There was a higher than expected frequency of first degree relatives affected with OCD. In addition, this study may support the hypothesis that OCD and tics are genetically related.
在墨西哥城的墨西哥精神医学研究所对27名强迫症（OCD）患者进行了研究。这是拉丁美洲研究的首批强迫症患者样本。男性和女性在性别比例以及所表现出的强迫观念和强迫行为类型上存在显著差异。共病数据显示，强迫型人格障碍、抑郁症、性虐待、自杀未遂和神经损伤的发生率很高。大约三分之一的强迫症病例显示出阳性家族史。患有强迫症的一级亲属的频率高于预期。此外，这项研究可能支持强迫症与抽动症在基因上相关的假说。
