Guo Y L, Lin C J, Yao W J, Ryan J J, Hsu C C
Department of Environmental and Occupational Health, National Cheng Kung University Medical Center, Taiwan, Republic of China.
J Toxicol Environ Health. 1994 Jan;41(1):83-93. doi: 10.1080/15287399409531828.
Fifty-five Yu-Cheng (oil-disease) children born between 1978 and 1985 to mothers who ate PCB-contaminated rice oil in 1978-1979 were studied and compared to age- and sex-matched control subjects in 1991. The children's growth profiles, bone mineral density and soft tissue composition, joint laxity, and serum parathyroid hormone, vitamin D, calcium, alkaline phosphatase, and phosphate were compared. The Yu-Cheng children were 3.1 cm (p < .05) smaller and had less total lean mass and soft tissue mass as compared to the matched control subjects. All other parameters studied were similar in both groups. The shorter height and decreased total lean mass and soft tissue content were only seen in the Yu-Cheng children who were the first born after the ingestion, but not in subsequent children. This was most likely due to decreased body burdens of the PCBs and related contaminants over time in the mothers.
对1978年至1985年间出生的55名油症儿童进行了研究，这些儿童的母亲在1978 - 1979年食用了受多氯联苯污染的米糠油，并于1991年与年龄和性别匹配的对照对象进行比较。比较了儿童的生长情况、骨矿物质密度和软组织成分、关节松弛度以及血清甲状旁腺激素、维生素D、钙、碱性磷酸酶和磷酸盐。与匹配的对照对象相比，油症儿童身高矮3.1厘米（p <.05），总瘦体重和软组织质量较低。两组研究的所有其他参数相似。身高较矮以及总瘦体重和软组织含量降低仅在摄入污染物后首个出生的油症儿童中出现，在随后出生的儿童中未出现。这很可能是由于随着时间推移，母亲体内多氯联苯及相关污染物的身体负担降低所致。
