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一种新开发的生物玻璃陶瓷的制备及体内评价

Preparation and in vivo evaluation of a newly developed bioglass ceramic.

作者信息

Lin F H, Liu H C, Hon M H, Wang C Y

机构信息

Center for Biomedical Engineering, College of Medicine, National Taiwan University, Taipei, ROC.

出版信息

J Biomed Eng. 1993 Nov;15(6):481-6. doi: 10.1016/0141-5425(93)90063-5.

DOI:10.1016/0141-5425(93)90063-5
PMID:8277753
Abstract

This paper presents details of the fabrication of a glass ceramic, and its application as an artificial bone prosthetic material. This new bioglass ceramic, with composition of Na2O 8.4%, CaO 40.6%, P2O5 12% and SiO2 39%, had 160-190 MPa and 800-980 MPa of three-point bending strength and compressive strength respectively. The ceramic has a (Na, Ca) (P, Si) O3 crystalline phase with a uniform crystal size of about 10 microns, which was attributed to the high nucleation frequency. The rabbit condyle test showed that the material formed a tight chemical bond with biological texture and had good biocompatibility.

摘要

本文介绍了一种玻璃陶瓷的制备细节及其作为人工骨修复材料的应用。这种新型生物玻璃陶瓷的组成成分为Na2O 8.4%、CaO 40.6%、P2O5 12%和SiO2 39%,其三点弯曲强度和抗压强度分别为160 - 190MPa和800 - 980MPa。该陶瓷具有(Na, Ca)(P, Si)O3晶相,晶体尺寸均匀,约为10微米,这归因于高成核频率。兔髁突试验表明,该材料与生物组织形成了紧密的化学键,具有良好的生物相容性。

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