红褐乳菇中的新型细胞毒性物质——红褐乳菌素B、C、D、E和F。
Russuphelins B, C, D, E and F, new cytotoxic substances from the mushroom Russula subnigricans Hongo.
作者信息
Takahashi A, Agatsuma T, Ohta T, Nunozawa T, Endo T, Nozoe S
机构信息
Faculty of Pharmaceutical Sciences, Tohoku University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1993 Oct;41(10):1726-9. doi: 10.1248/cpb.41.1726.
PMID:8281571
Abstract
Five new chlorinated phenyl ethers, russuphelins B (2), C (3), D (4), E (5) and F (6) have been isolated from the mushroom Russula subnigricans Hongo, and their structures were elucidated by spectroscopic and chemical means. Russuphelins B (2), C (3) and D (4) exhibited cytotoxic activity in vitro against P388 leukemia cells.
摘要
从蘑菇亚黑红菇（Russula subnigricans Hongo）中分离出了五种新的氯化苯醚，即红菇素B（2）、C（3）、D（4）、E（5）和F（6），并通过光谱和化学方法阐明了它们的结构。红菇素B（2）、C（3）和D（4）在体外对P388白血病细胞表现出细胞毒性活性。
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