Takahashi A, Agatsuma T, Matsuda M, Ohta T, Nunozawa T, Endo T, Nozoe S
Faculty of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Chem Pharm Bull (Tokyo). 1992 Dec;40(12):3185-8. doi: 10.1248/cpb.40.3185.
A new cytotoxic substance, designated russuphelin A (1), has been isolated from the mushroom Russula subnigricans Hongo (Basidiomycetes). The structure was elucidated as 2,6-bis(2,6-dichloro-4-hydroxyphenyloxy)-1,4-dimethoxy-benzene on the basis of spectroscopic data and confirmed by total synthesis.
从蘑菇亚黑红菇(担子菌纲)中分离出一种新的细胞毒性物质,命名为红菇素A(1)。根据光谱数据确定其结构为2,6-双(2,6-二氯-4-羟基苯氧基)-1,4-二甲氧基苯,并通过全合成进行了确认。