Meselhy M R, Kadota S, Momose Y, Hatakeyama N, Kusai A, Hattori M, Namba T
Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmaceutical University, Japan.
Chem Pharm Bull (Tokyo). 1993 Oct;41(10):1796-802. doi: 10.1248/cpb.41.1796.
Two new quinochalcone C-glycosides, hydroxysafflor yellow A (1a) and tinctormine (2a), were isolated from Carthamus tinctorius L. (Compositae) together with carthamin, safflor yellow B and safflomin C. The structures of 1a and 2a have been determined by spectroscopic methods including heteronuclear multiple-bond multiple-quantum coherence and linked scan FAB-MS. The latter compound (2a) was demonstrated to have potent Ca2+ antagonistic action.
从菊科植物红花（Carthamus tinctorius L.）中分离出两种新的喹诺查耳酮C-糖苷，即羟基红花黄色素A（1a）和紫红素（2a），同时还分离出了红花苷、红花黄色素B和红花素C。通过包括异核多键多量子相干和连接扫描快原子轰击质谱在内的光谱方法确定了1a和2a的结构。已证明后一种化合物（2a）具有有效的Ca2+拮抗作用。
