Fijten G H, Muris J W, Starmans R, Knottnerus J A, Blijham G H, Krebber T F
Diagnostic Coordination Centre, University Hospital Maastricht, The Netherlands.
Fam Pract. 1993 Sep;10(3):283-7. doi: 10.1093/fampra/10.3.283.
The objective of the studies reported in this paper was to determine the incidence as well as the final diagnostic outcome of rectal bleeding presenting in general practice. Because of the wide variety observed in incidence rates among 83 general practitioners (GPs) in the first study (A) an additional study (B) was undertaken. In study B with 10 GPs special efforts were made to maximize the catchment rate. The mean 'consultation incidence rate' was 7 per 1000 people per year. A follow-up period of at least 1 year was applied to establish the final diagnostic conclusion. Occurrence of colorectal cancer was found in 3% of patients with rectal bleeding. This may represent an overestimation of the prior probability since there was a selection in favour of patients with clinically relevant rectal bleeding. In about 90% of patients rectal bleeding was related to minor ailments or self-limiting disorders. Further study on predictive values of (combinations of) other signs and symptoms is necessary to develop clinical recommendations.
本文所报告的研究目的是确定全科医疗中出现直肠出血的发生率以及最终诊断结果。由于在第一项研究(A)中,83名全科医生(GP)观察到的发病率差异很大,因此开展了另一项研究(B)。在研究B中,10名全科医生做出了特别努力以最大化收集率。平均“会诊发病率”为每年每1000人中有7例。应用至少1年的随访期来确定最终诊断结论。在直肠出血患者中,3%被发现患有结直肠癌。这可能高估了先验概率,因为存在对具有临床相关直肠出血患者的选择偏倚。在约90%的患者中,直肠出血与小病或自限性疾病有关。有必要进一步研究其他体征和症状(的组合)的预测价值,以制定临床建议。