Hirano H, Hirahara K, Asakura T, Shimozuru T, Kadota K, Kasamo S, Shimohonji M, Kimotsuki K, Goto M
Department of Neurosurgery, University of Kagoshima, Japan.
J Neurosurg. 1994 Feb;80(2):321-3. doi: 10.3171/jns.1994.80.2.0321.
A case is reported of hydrocephalus due to overproduction of cerebrospinal fluid (CSF) caused by villous hypertrophy of the choroid plexus in the lateral ventricles. A 7-year-old girl with mental retardation developed gait disturbance; hydrocephalus and a Dandy-Walker cyst were detected on computerized tomography. She was initially treated with a ventriculoperitoneal shunt; however, shunting failed to control the hydrocephalus. The excessive outflow of CSF suggested choroid plexus abnormality, and magnetic resonance (MR) imaging revealed enlargement of the choroid plexus in both lateral ventricles. The patient was therefore diagnosed as having hydrocephalus induced by overproduction of CSF, which was controlled by resection of the choroid plexus. Histological examination showed the structure typical of normal choroid plexus. This is a rare case of villous hypertrophy of the choroid plexus in which MR imaging assisted in the diagnosis.
报告了一例因侧脑室脉络丛绒毛肥大导致脑脊液（CSF）分泌过多而引起脑积水的病例。一名患有智力障碍的7岁女孩出现步态障碍；计算机断层扫描发现脑积水和Dandy-Walker囊肿。她最初接受了脑室腹腔分流术治疗；然而，分流未能控制脑积水。脑脊液的过度流出提示脉络丛异常，磁共振（MR）成像显示双侧脑室脉络丛增大。因此，该患者被诊断为脑脊液分泌过多所致脑积水，通过切除脉络丛得以控制。组织学检查显示为正常脉络丛的典型结构。这是一例罕见的脉络丛绒毛肥大病例，其中MR成像有助于诊断。
