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饮食核苷酸的非免疫系统反应。

Nonimmune system responses to dietary nucleotides.

作者信息

Uauy R

机构信息

Institute of Nutrition and Food Technology, University of Chile, Santiago.

出版信息

J Nutr. 1994 Jan;124(1 Suppl):157S-159S. doi: 10.1093/jn/124.suppl_1.157S.

DOI:10.1093/jn/124.suppl_1.157S
PMID:8283307
Abstract

Studies have demonstrated that a fecal flora with a predominance of bifidobacteria develops in infants fed a nucleotide-supplemented commercial formula, closer to that in breast-fed infants. In contrast, enterobacteria predominate in the fecal flora of infants fed an unsupplemented formula. When given parenterally, nucleotides promote recovery from injuries caused by hepatotoxic agents. These results suggest that dietary nucleotides may potentially play a significant role in nutrition.

摘要

研究表明,食用添加核苷酸的商业配方奶粉的婴儿,其粪便菌群中双歧杆菌占优势,更接近母乳喂养婴儿的情况。相比之下,食用未添加配方奶粉的婴儿粪便菌群中肠杆菌占主导。经肠胃外给药时,核苷酸可促进肝毒性药物所致损伤的恢复。这些结果表明,膳食核苷酸可能在营养方面发挥重要作用。

相似文献

1
Nonimmune system responses to dietary nucleotides.饮食核苷酸的非免疫系统反应。
J Nutr. 1994 Jan;124(1 Suppl):157S-159S. doi: 10.1093/jn/124.suppl_1.157S.
2
Dietary nucleotides: cellular immune, intestinal and hepatic system effects.膳食核苷酸:对细胞免疫、肠道及肝脏系统的影响
J Nutr. 1994 Jan;124(1 Suppl):144S-148S. doi: 10.1093/jn/124.suppl_1.144S.
3
Diet and faecal flora in the newborn: nucleotides.新生儿的饮食与粪便菌群:核苷酸
Arch Dis Child Fetal Neonatal Ed. 1994 Mar;70(2):F137-40. doi: 10.1136/fn.70.2.f137.
4
Dietary nucleotides influence lipoprotein metabolism in newborn infants.膳食核苷酸影响新生儿的脂蛋白代谢。
Pediatr Res. 1994 Jan;35(1):112-6. doi: 10.1203/00006450-199401000-00023.
5
Prospects for further approximation of infant formulas to human milk.婴儿配方奶粉进一步接近母乳的前景。
Hum Nutr Appl Nutr. 1986;40 Suppl 1:27-37.
6
The role of dietary nucleotides in neonatal and infant nutrition.膳食核苷酸在新生儿和婴儿营养中的作用。
Singapore Med J. 1998 Apr;39(4):145-50.
7
[Development of intestinal flora in neonates].[新生儿肠道菌群的发育]
Hokkaido Igaku Zasshi. 1987 Dec;62(6):895-906.
8
Scientific rationale and benefits of nucleotide supplementation of infant formula.
J Paediatr Child Health. 2002 Dec;38(6):543-9. doi: 10.1046/j.1440-1754.2002.00056.x.
9
Supplementation of milk formula with galacto-oligosaccharides improves intestinal micro-flora and fermentation in term infants.在足月婴儿的配方奶中添加低聚半乳糖可改善肠道微生物群和发酵情况。
Chin Med J (Engl). 2004 Jun;117(6):927-31.
10
Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants.母乳喂养和人工喂养婴儿新生儿期肠道菌群的发育及差异
Pediatrics. 1983 Sep;72(3):317-21.

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