Wilson T G, Moreno J G, Weinberg A, Ahlering T E
Department of Urology and Urologic Oncology, City of Hope National Medical Center, Duarte, California.
J Urol. 1994 Feb;151(2):331-4. doi: 10.1016/s0022-5347(17)34940-6.
The modified Indiana pouch is currently an accepted and widely used form of continent cutaneous urinary diversion. However, results of long-term followup and potential late complications are still being established. We report our experience with 130 modified Indiana pouches performed between September 1987 and September 30, 1991. In 16 patients (12%) late complications developed between 1 and 16 months after the pouch procedure. Ureteral obstruction developed in 9 of these patients (7%), including bilateral obstruction in 4. Balloon dilation with or without incision of ureteral strictures in 6 patients resulted in an 83% failure rate, while ureteral reimplantation was successful in 91% (10 of 11 cases). Reservoir dysfunction was the late complication in the remaining 7 patients. Urodynamic evaluation was essential in determining appropriate treatment for incontinence with either replication of the ileal segment or pouch augmentation with an ileal patch. Of the 16 late complications 56% occurred in patients who received between 3,000 and 6,500 rad of pelvic radiation before the urinary diversion. We conclude that the modified Indiana pouch is a successful form of urinary diversion with an acceptable complication rate. Ureteral balloon dilation with or without endoscopic incision of ureteral strictures has not been successful. However, patients can usually undergo successful ureteral reimplantation via an extraperitoneal approach with minimal morbidity. Previously radiated patients are at higher risk for complications and require shorter ureteral tunnels to avoid stricture, in addition to an ileal patch at initial construction.
改良印第安纳袋目前是一种被认可且广泛应用的可控性皮肤尿流改道术式。然而,长期随访结果及潜在的晚期并发症仍在研究之中。我们报告了1987年9月至1991年9月30日期间实施的130例改良印第安纳袋手术的经验。16例患者(12%)在造袋术后1至16个月出现晚期并发症。其中9例患者(7%)发生输尿管梗阻,包括4例双侧梗阻。6例患者对输尿管狭窄进行了带或不带切开的球囊扩张,失败率达83%,而输尿管再植术成功率为91%(11例中的10例)。其余7例患者出现储尿囊功能障碍。尿动力学评估对于确定采用回肠段复制或回肠补片扩大储尿囊治疗尿失禁的合适方法至关重要。在这16例晚期并发症中,56%发生在尿流改道前接受3000至6500拉德盆腔放疗的患者中。我们得出结论,改良印第安纳袋是一种成功的尿流改道术式,并发症发生率可接受。带或不带输尿管狭窄内镜下切开的输尿管球囊扩张术未取得成功。然而,患者通常可通过腹膜外途径成功进行输尿管再植术,且发病率极低。既往接受过放疗的患者并发症风险更高,除了在初次构建时使用回肠补片外,还需要较短的输尿管隧道以避免狭窄。