Quinn S F, Franzini D A, Demlow T A, Rosencrantz D R, Kim J, Hanna R M, Szumowski J
Department of Radiology, Good Samaritan Hospital and Medical Center, Portland, OR 97210.
Radiology. 1994 Feb;190(2):323-7. doi: 10.1148/radiology.190.2.8284376.
To evaluate the diagnostic accuracy of magnetic resonance (MR) imaging in staging prostate cancer with an endorectal surface coil technique.
The authors prospectively evaluated MR images obtained with an endorectal surface coil from 70 consecutive patients with known prostate cancer. Gadopentetate dimeglumine was administered to 40 patients. Multiple sequences were used, including conventional and fast spin echo, with and without fat suppression. The readers were blinded to the MR findings unless bone or nodal metastasis was present. MR images were compared with whole-mount sections.
The prospective staging accuracy for MR imaging was 51% (36 of 70 patients). Stage B disease was present in 27 patients (38%), stage C in 42 (60%), and stage D in one (1%). The retrospective staging accuracy was 67% (47 of 70 patients). Of the 42 patients with stage C disease, positive surgical margins were present in 36 (85%). Gadopentetate dimeglumine did not help detect or stage tumors.
Further studies must be performed to determine the role of endorectal coil MR imaging in the staging of prostate cancer.
采用直肠内表面线圈技术评估磁共振(MR)成像在前列腺癌分期中的诊断准确性。
作者前瞻性地评估了70例连续已知前列腺癌患者采用直肠内表面线圈获得的MR图像。40例患者使用了钆喷酸葡胺。采用了多种序列,包括常规和快速自旋回波序列,有无脂肪抑制。除非存在骨或淋巴结转移,阅片者对MR检查结果不知情。将MR图像与全层切片进行比较。
MR成像的前瞻性分期准确性为51%(70例患者中的36例)。27例患者(38%)为B期疾病,42例(60%)为C期,1例(1%)为D期。回顾性分期准确性为67%(70例患者中的47例)。在42例C期疾病患者中,36例(85%)手术切缘阳性。钆喷酸葡胺无助于检测或分期肿瘤。
必须进行进一步研究以确定直肠内线圈MR成像在前列腺癌分期中的作用。