Kinnula V L, Sovijärvi A R
Department of Pulmonary Medicine, Helsinki University Central Hospital, Finland.
Respiration. 1993;60(5):273-8. doi: 10.1159/000196215.
In hyperventilation syndrome (HVS), hyperventilation is often provoked by exercise. This study was undertaken to investigate gas exchange parameters and their correlation to arterial blood gas values in HVS patients during exercise. Ventilatory equivalents for oxygen (VE/VO2) and carbon dioxide (VE/VCO2) were significantly higher in HVS patients than in the controls. (VE/VO2) during light exercise (40-50 W) was 23.1 +/- 2.7 (n = 10) in the controls and 35.2 +/- 8.2 (n = 10) in the HVS group (p < 0.01). VE/VCO2 during light exercise was 30.0 +/- 3.3 in the controls and 41.8 +/- 6.0 in the HVS group (p < 0.01). In HVS, significantly correlations were observed between VE/VCO2 and PaCO2, and between VE/VO2 and PaCO2 during both light and maximal exercise (p < 0.02). The findings suggest that exercise testing can be used to aid HVS diagnosis without invasive arterial cannulation.
在过度通气综合征（HVS）中，过度通气常由运动诱发。本研究旨在调查HVS患者运动期间的气体交换参数及其与动脉血气值的相关性。HVS患者的氧通气当量（VE/VO2）和二氧化碳通气当量（VE/VCO2）显著高于对照组。对照组在轻度运动（40 - 50瓦）时的（VE/VO2）为23.1±2.7（n = 10），HVS组为35.2±8.2（n = 10）（p < 0.01）。轻度运动时的VE/VCO2在对照组为30.0±3.3，在HVS组为41.8±6.0（p < 0.01）。在HVS中，轻度运动和最大运动期间，VE/VCO2与PaCO2之间以及VE/VO2与PaCO2之间均观察到显著相关性（p < 0.02）。这些发现表明，运动测试可用于辅助HVS诊断，而无需进行有创动脉插管。
