Manninen M P
Department of Clinical Medicine, University of Tampere, Finland.
Eur Arch Otorhinolaryngol. 1993;250(7):383-6. doi: 10.1007/BF00180381.
Of all the 95 primary tracheal carcinomas diagnosed in Finland in 1967-1985, 72% were squamous cell carcinomas. Fifty-three percent were located in the lower third of the trachea. main symptoms were dyspnea, cough and hemoptysis. Fifty-nine percent of the patients developed extratracheal growth during the follow-up of 12 years, with lungs, neck, liver, and bones being the most common sites. In addition, autopsy revealed mediastinal metastases in 25% of patients. Vocal cord palsy at the time of diagnosis was present in 33%. The size and location of tumor in the trachea did not affect survival significantly. Patients with adenoid cystic carcinomas had the best prognosis.
在1967年至1985年芬兰诊断出的95例原发性气管癌中,72%为鳞状细胞癌。53%位于气管下三分之一处。主要症状为呼吸困难、咳嗽和咯血。在12年的随访中,59%的患者出现气管外生长,肺部、颈部、肝脏和骨骼是最常见的部位。此外,尸检发现25%的患者有纵隔转移。诊断时33%的患者存在声带麻痹。肿瘤在气管中的大小和位置对生存率没有显著影响。腺样囊性癌患者的预后最好。