Kempley S T, Gamsu H R
Children Nationwide Regional Neonatal Centre, King's College Hospital, London, UK.
Early Hum Dev. 1993 Oct;34(3):227-32. doi: 10.1016/0378-3782(93)90180-3.
In order to determine the relationship between blood pressure and arterial blood flow velocity in various regional circulations, Doppler ultrasound measurements of blood flow velocity were recorded on the first day of postnatal life from the anterior cerebral (ACA), superior mesenteric, coeliac axis and left renal artery. In 34 ventilated very low birth weight (VLBW) infants, results were correlated with arterial blood pressure and blood gases in a multiple regression model. ACA velocity was correlated with blood pressure (r = 0.70) and PaCO2 (r = 0.64), but there was no relationship between blood pressure and velocity in the other arteries. Repeated measurements were performed at one week of age in 15 infants. Blood flow velocity in the cerebral and renal arteries was related to blood pressure; velocity in the cerebral arteries was inversely correlated with PaO2 and velocity in the coeliac and mesenteric arteries was positively correlated with PaO2. In VLBW infants on the first day of life, blood flow velocity is related to blood pressure in the cerebral circulation only.
为了确定不同区域循环中血压与动脉血流速度之间的关系，在出生后第一天，使用多普勒超声对大脑前动脉（ACA）、肠系膜上动脉、腹腔动脉和左肾动脉的血流速度进行了测量。在34例接受通气的极低出生体重（VLBW）婴儿中，将测量结果与动脉血压和血气指标纳入多元回归模型进行相关性分析。ACA血流速度与血压（r = 0.70）和动脉血二氧化碳分压（PaCO2，r = 0.64）相关，但其他动脉的血压与血流速度之间无相关性。对15例婴儿在1周龄时进行了重复测量。脑动脉和肾动脉的血流速度与血压有关；脑动脉血流速度与动脉血氧分压（PaO2）呈负相关，腹腔动脉和肠系膜上动脉血流速度与PaO2呈正相关。在出生第一天的VLBW婴儿中，血流速度仅与脑循环中的血压有关。
