Järvholm B, Larsson S, Hagberg S, Olling S, Ryd W, Torén K
Dept. of Occupational Medicine, Sahlgrenska Hospital, St. Sigfridsg, Göteborg, Sweden.
Eur Respir J. 1993 Oct;6(9):1271-5.
We wanted to assess the quantitative importance of asbestos as a cause of lung cancer. In a case-referent study, the exposure to asbestos, tobacco smoke and some other occupational exposures were compared between 147 cases of lung cancer (100 men, 47 women), 111 hospital referents, and 109 population referents, all below the age of 75 yrs and living in an industrial city. The attributable risk of lung cancer due to asbestos exposure was 16% in men (95% confidence interval 1-31%). No woman had occupational exposure to asbestos. We conclude that in the mid 1980's tobacco smoking was the major attributable risk, being 95% for men and 78% for women, but that in men asbestos was an appreciable contributing factor in the general population of a Swedish industrial city.
我们想要评估石棉作为肺癌病因的定量重要性。在一项病例对照研究中，对147例肺癌患者（100名男性，47名女性）、111名医院对照者和109名人群对照者（均年龄在75岁以下且居住在一个工业城市）的石棉暴露、烟草烟雾暴露及其他一些职业暴露情况进行了比较。男性因石棉暴露导致肺癌的归因风险为16%（95%置信区间1%-31%）。没有女性有职业性石棉暴露。我们得出结论，在20世纪80年代中期，吸烟是主要的归因风险因素，男性为95%，女性为78%，但在瑞典一个工业城市的普通人群中，石棉对男性来说是一个相当重要的促成因素。
