Downey R, Perkin R M, MacQuarrie J
Pulmonary Section 111P, Jerry L. Petitis Memorial Veterans Hospital, Loma Linda, CA 92357.
Sleep. 1993 Oct;16(7):620-3. doi: 10.1093/sleep/16.7.620.
Upper airway resistance syndrome (UARS) appears to be underrecognized or at least underreported in the medical literature. We have found that these children may suffer the same, if not more, severe consequences of sleep disordered breathing than obstructive sleep apnea patients. Seventy-five infants and children were age and gender matched from a heterogeneous patient population in Southern California. Each patient underwent clinical polysomnography. Twenty-five patients were in each of three groups. Group one patients were clinician referred to the sleep clinic and were found to be free of significant sleep pathology. Group two patients had UARS. Group three patients had frank obstructive sleep apnea. The three groups differed on respiratory, sleep and snoring parameters. A heuristic is presented to help clinicians tailor their treatment approach and sleep scientists to test the model to aid in the understanding of UARS.
上气道阻力综合征（UARS）在医学文献中似乎未得到充分认识，或者至少报道不足。我们发现，这些儿童即使不比阻塞性睡眠呼吸暂停患者遭受更多，也可能遭受同样严重的睡眠呼吸障碍后果。从南加州不同患者群体中选取了75名年龄和性别匹配的婴幼儿及儿童。每位患者均接受了临床多导睡眠图检查。将患者分为三组，每组25人。第一组患者由临床医生转诊至睡眠诊所，经检查未发现明显的睡眠病理问题。第二组患者患有上气道阻力综合征。第三组患者患有明显的阻塞性睡眠呼吸暂停。三组在呼吸、睡眠和打鼾参数方面存在差异。本文提出一种启发式方法，以帮助临床医生调整治疗方法，并帮助睡眠科学家测试该模型，以加深对UARS的理解。
