Rush P J, Wong J S, Kirsh J, Devlin M
Department of Medicine, University of Toronto, Canada.
Arch Phys Med Rehabil. 1994 Jan;75(1):112-5.
Using dual energy x-ray absorptiometry, we studied 16 male patients with unilateral above knee amputations (AKA) with a mean age of 48 years (range, 23 to 66 years) who were full-time prosthetic users for more than 5 years. All prostheses were ischial weight bearing. All 16 subjects were found to have normal bone density in their spines and in the normal femurs when compared to nonamputation controls. However, a significant decrease of mean femoral neck bone density was found on the amputated side (0.68g/cm2, range, 0.52 to 1.01) when compared to the normal side (1.01g/cm2, range, 0.75 to 1.20) (p < .05). The mean bone density percentage difference between the two sides was 28% (range, 4% to 48%). There was a significantly negative correlation between the patient's age at the time of amputation and the severity of osteopenia (-0.73; p < 0.05).
我们使用双能X线吸收法对16例单侧膝上截肢（AKA）男性患者进行了研究，这些患者平均年龄48岁（范围23至66岁），已使用全假肢超过5年。所有假肢均为坐骨承重。与未截肢对照组相比，所有16名受试者的脊柱和正常股骨骨密度均正常。然而，与正常侧（1.01g/cm²，范围0.75至1.20）相比，截肢侧的平均股骨颈骨密度显著降低（0.68g/cm²，范围0.52至1.01）（p < 0.05）。两侧骨密度的平均百分比差异为28%（范围4%至48%）。截肢时患者的年龄与骨质减少的严重程度之间存在显著负相关（-0.73；p < 0.05）。
