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[切尔诺贝利核电站事故后辐射诱发甲状腺疾病的牛血细胞中钙代谢的改变]

[Modification of Ca2+ metabolism in the blood cells of cattle with radiation-induced thyroid disorder after the Chernobyl nuclear power plant accident].

作者信息

Shevchenko A S, Kobialko V O, Shevchenko T S, Lazarev N M, Astasheva N P, Aleksakhin R M

出版信息

Radiats Biol Radioecol. 1993 Nov-Dec;33(6):775-82.

PMID:8293102
Abstract

Increasing of Ca2+ concentration in cytoplasm and of the rate of 45Ca iflux into cows erythrocytes in 19-24 month after Chernobyl accident was revealed. Correlation between Ca2+ concentration in cytoplasm of erythrocytes and thyroxin content in plasma of cows with radioiodine damage of thyroid gland was found. Reduction of the rate of 45Ga influx into erythrocytes in cows with radiation doses of 20-60 By on thyroid gland was shown in later time after accident (3-5 years). Changes in Ca2+ permeability through membranes of erythrocytes and neutrophils after injection of 131I into calves in doses of 300 Gy and more on thyroid gland was found.

摘要

在切尔诺贝利事故发生后的19 - 24个月,发现奶牛红细胞胞质中Ca2+浓度升高以及45Ca流入速率增加。发现甲状腺受到放射性碘损伤的奶牛,其红细胞胞质中Ca2+浓度与血浆中甲状腺素含量之间存在相关性。事故发生后的后期(3 - 5年),显示甲状腺接受20 - 60贝可辐射剂量的奶牛红细胞中45Ga流入速率降低。发现给小牛甲状腺注射300戈瑞及以上剂量的131I后,红细胞和中性粒细胞膜的Ca2+通透性发生变化。

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