Moul J W, Schanne F J, Thompson I M, Frazier H A, Peretsman S A, Wettlaufer J N, Rozanski T A, Stack R S, Kreder K J, Hoffman K J
Urology Services, Walter Reed Army Medical Center, Washington, DC.
Cancer. 1994 Jan 15;73(2):388-93. doi: 10.1002/1097-0142(19940115)73:2<388::aid-cncr2820730225>3.0.co;2-q.
The rarity of testis tumor in black patients has made the study of a large series difficult. Much of the epidemiologic and clinical information regarding this neoplasm in this population is in dispute, including data on incidence, prognosis, histologic distribution, age and stage at presentation, and side distribution.
A retrospective review of 66 blacks with testicular tumors from seven military medical centers was performed.
Similar results were found for blacks with testis tumor to those of the general testis cancer population regarding prognosis, side distribution, and age of onset for nonseminoma and interstitial tumors. There is a slight increase in the expected number of interstitial tumors in blacks, but the distribution between seminoma and nonseminoma is similar to the general population. The mean age of presentation for seminoma in blacks was younger than that of the general testis cancer population. For testis tumor treated at the same institution, there was an increased delay of diagnosis in blacks compared with whites. The number of new cases of testicular cancer between 1979 and 1991 at one major center was increased for whites but not for blacks. The availability of cisplatin-based combination chemotherapy has resulted in an improved prognosis for blacks, as has already been demonstrated for white populations.
Testis tumor in blacks behaves similarly to testis tumor in the general population except that in blacks there are more interstitial tumors and the mean age of presentation for seminoma is younger. Further, there is an increased delay in diagnosis for blacks compared with whites, but the incidence of this tumor in this population does not appear to be increasing. Cisplatin-based chemotherapy has significantly improved survival in this population.
黑人患者睾丸肿瘤的罕见性使得对大量病例的研究变得困难。关于该人群中这种肿瘤的许多流行病学和临床信息存在争议，包括发病率、预后、组织学分布、就诊时的年龄和分期以及双侧分布的数据。
对来自七个军事医疗中心的66例患有睾丸肿瘤的黑人患者进行了回顾性研究。
在预后、双侧分布以及非精原细胞瘤和间质细胞瘤的发病年龄方面，患有睾丸肿瘤的黑人与一般睾丸癌人群的结果相似。黑人中间质细胞瘤的预期数量略有增加，但精原细胞瘤和非精原细胞瘤之间的分布与一般人群相似。黑人中精原细胞瘤的平均就诊年龄比一般睾丸癌人群年轻。在同一机构接受治疗的睾丸肿瘤患者中，黑人的诊断延迟比白人有所增加。1979年至1991年期间，一个主要中心白人睾丸癌新病例数量增加，而黑人则没有。基于顺铂的联合化疗已使黑人的预后得到改善，这在白人人群中也已得到证实。
黑人的睾丸肿瘤表现与一般人群的睾丸肿瘤相似，只是黑人中间质细胞瘤更多，精原细胞瘤的平均就诊年龄更年轻。此外，与白人相比，黑人的诊断延迟增加，但该人群中这种肿瘤的发病率似乎并未上升。基于顺铂的化疗显著提高了该人群的生存率。
