α链病及相关小肠淋巴瘤：一份备忘录
Alpha-chain disease and related small-intestinal lymphoma: a memorandum.
出版信息
Bull World Health Organ. 1976;54(6):615-24.
Abstract
Primary intestinal lymphomas are remarkably frequent in the Mediterranean region and South-West Asia. They are usually found in young persons from the lower socio-economic strata of the population. These conditions sometimes present a premalignant phase characterized by plasmacytic infiltration of the small intestine. It has been reported that early treatment of cases with antibiotics is followed by complete remission, suggesting that some environmental factors may be responsible for the disease. Some patients have an abnormal alpha-chain protein in their serum. This Memorandum reviews the present knowledge of the clinical, immunological, epidemiological, and therapeutic aspects of this condition.
摘要
原发性肠道淋巴瘤在地中海地区和西南亚极为常见。它们通常见于社会经济地位较低阶层的年轻人。这些病症有时会呈现出一个以小肠浆细胞浸润为特征的癌前阶段。据报道，用抗生素对这些病例进行早期治疗后会完全缓解，这表明某些环境因素可能是该病的病因。一些患者血清中存在异常的α链蛋白。本备忘录综述了关于这种病症的临床、免疫学、流行病学和治疗方面的现有知识。
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Alpha-chain disease and related small-intestinal lymphoma: a memorandum.α链病及相关小肠淋巴瘤：一份备忘录
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Detection in normal plasma of immunoglobulin resembling the protein of gamma-chain disease.在正常血浆中检测到类似γ链病蛋白的免疫球蛋白。
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