Umeki S
Department of Medicine, Toshida-kai Kumeda Hospital.
Kansenshogaku Zasshi. 1993 Dec;67(12):1172-7. doi: 10.11150/kansenshogakuzasshi1970.67.1172.
Mechanisms for purple discoloration of the plastic urine bag in purple urine bag syndrome (PUBS) were investigated. Activities of bacterial indoxyl sulfatase catalyzing the conversion of indoxyl sulfate to indigo (or indirubin) were detected in strong alkaline liquid media but not in normal ones. These enzyme activities were particularly high in simple and combined cultures of Proteus mirabilis and/or Klebsiella pneumoniae. These results suggest that occurrence of PUBS is associated with strong alkaline urine as well as urinary tract infections induced by some species of bacteria with indoxyl sulfatase.
对紫色尿袋综合征（PUBS）中塑料尿袋出现紫色变色的机制进行了研究。在强碱性液体培养基中检测到了催化硫酸吲哚酚转化为靛蓝（或靛玉红）的细菌吲哚酚硫酸酯酶的活性，而在正常培养基中未检测到。这些酶活性在奇异变形杆菌和/或肺炎克雷伯菌的单纯培养和混合培养中特别高。这些结果表明，PUBS的发生与强碱性尿液以及由某些具有吲哚酚硫酸酯酶的细菌引起的尿路感染有关。
