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[对巴黎母婴福利中心监测的1至3岁儿童铅中毒筛查策略的评估]

[Evaluation of the screening strategy for lead poisoning in 1-to-3-year-old children monitored in maternal-child welfare centers in Paris].

作者信息

Alfaro C, Vincelet C, Lombrail P, Delour M, Squinazi F, Fontaine A, Gottot S, Brodin M

机构信息

Service de Santé Publique de l'Hôpital R. Debré, Paris.

出版信息

Rev Epidemiol Sante Publique. 1993;41(6):473-9.

PMID:8296033
Abstract

A procedure for screening for lead poisoning was implemented since 1987 in the maternal and child health centers of 6 Paris "arrondissements". It relies on a screening of the children through environmental and clinical information. Our study aimed at evaluating this procedure and at estimating the prevalence of lead poisoning in the children aged 1 to 3 years old attending free maternal and child health centers in Paris. We did a cross-sectional survey of a sample of 512 children. A questionnaire concerning each child's risk factors was answered by the paediatric nurses of the clinics. Potential lead poisoning cases were detected by capillary determining of free erythrocyte protoporphyrins (FEP). Blood lead level (PbB) was measured in children with FEP > or = 350 micrograms/l. The prevalence rate of lead poisoning was estimated at 1.9% +/- 1.7% for a PbB threshold > or = 250 micrograms/l and at 9.6% +/- 3.5% for a PbB threshold > or = 150 micrograms/l. The detection procedure identified 4 children out of 5 with a PbB > or = 250 micrograms/l and 2 children out of 3 with a PbB > or = 150 micrograms/l.

摘要

自1987年起,巴黎6个区的母婴健康中心实施了一项铅中毒筛查程序。该程序通过环境和临床信息对儿童进行筛查。我们的研究旨在评估这一程序,并估算在巴黎免费母婴健康中心就诊的1至3岁儿童中铅中毒的患病率。我们对512名儿童样本进行了横断面调查。诊所的儿科护士填写了一份关于每个儿童风险因素的问卷。通过毛细血管测定游离红细胞原卟啉(FEP)来检测潜在的铅中毒病例。对FEP≥350微克/升的儿童测量血铅水平(PbB)。对于PbB阈值≥250微克/升,铅中毒患病率估计为1.9%±1.7%;对于PbB阈值≥150微克/升,铅中毒患病率估计为9.6%±3.5%。该检测程序识别出了5名PbB≥250微克/升儿童中的4名,以及3名PbB≥150微克/升儿童中的2名。

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