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[地西泮影响下中枢神经系统功能与心率及呼吸节律的耦合行为]

[Coupling behavior of central nervous system functions as well as heart rate and respiratory rhythm under the influence of diazepam].

作者信息

Amenda G, Fitzke S, Sinz R

出版信息

Psychiatr Neurol Med Psychol Beih. 1975;20-21:57-61.

PMID:829637
Abstract

In order to substantiate the subjective feeling of relaxation and mental balance felt after taking Diazepam a new biorhythmometric technique was used, in which the minute-rhythm pulsations were calculated with the aid of autocorrelation analysis from the time series of central nervous functions and cardiorespiratory functions, and their frequency synchronisation recorded as to quantity in the form of a coupling factor. Proof of an improved central nervous co-ordination was that the coupling factor of a relatively uniform test team, all students, after administration of Diazepam (Faustan) was significantly higher than before. If one assumes that the psychosomatic illness, for which the use of Diazepam is considered advisable, are a manifestation of generally disturbed central nervous vegetative reaction condition, then the biorhythmometric survey of the internal co-ordination of relevant physiological functions provides stronger proof than testing with single parameters, between which we also found significant variations (for example, prolongation of the sensorimotor reaction times under Faustan).

摘要

为了证实服用地西泮后所感受到的放松和心理平衡的主观感觉,采用了一种新的生物节律测量技术,即通过自相关分析从中枢神经功能和心肺功能的时间序列中计算每分钟节律搏动,并将其频率同步以耦合因子的形式记录数量。中枢神经协调改善的证据是,在服用地西泮(法斯他)后,一个相对统一的测试团队(所有学生)的耦合因子明显高于服药前。如果假定使用地西泮被认为合适的身心疾病是中枢神经植物性反应状态普遍紊乱的一种表现,那么对相关生理功能内部协调性的生物节律测量调查比用单一参数测试能提供更强的证据,我们也发现单一参数之间存在显著差异(例如,服用法斯他后感觉运动反应时间延长)。

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