Martínez J P, López-Ribot J L, Chaffin W L
Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock 79430.
Infect Immun. 1994 Feb;62(2):709-12. doi: 10.1128/iai.62.2.709-712.1994.
As detected by indirect immunofluorescence and confocal microscopy, fibrinogen binding was heterogeneously distributed on the surface of Candida albicans. A low level of binding was generally observed homogeneously distributed on some yeast and most hyphal extensions of germ tubes. However, on most hyphal extensions, there were randomly distributed areas of increased expression, as revealed by patches of greater fluorescence intensity.
通过间接免疫荧光和共聚焦显微镜检测发现，纤维蛋白原结合在白色念珠菌表面呈异质性分布。在一些酵母和大多数芽管的菌丝延伸部分通常观察到低水平的结合，且呈均匀分布。然而，在大多数菌丝延伸部分，存在随机分布的表达增加区域，表现为荧光强度更高的斑块。
