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雾化维拉帕米和硝苯地平对支气管哮喘的影响。

Effect of aerosolised verapamil and nifedipine in bronchial asthma.

作者信息

Gupta S, Meena H S, Chopra R, Bidani R

机构信息

Department of Medicine, Lady Hardinge Medical College, New Delhi.

出版信息

J Assoc Physicians India. 1993 Jul;41(7):425-7.

PMID:8300487
Abstract

Twenty patients of bronchial asthma were given 5 mg of either nifedipine or verapamil as aerosol therapy in a randomized fashion. Both drugs showed a statistically significant improvement in FVC, PEFR at zero hours lasting through 90-120 minutes. Changes in respiratory rate, pulse rate, blood pressure were insignificant with verapamil while appreciable tachycardia and transient fall in BP occurred with nifedipine therapy.

摘要

20例支气管哮喘患者被随机给予5毫克硝苯地平或维拉帕米进行雾化治疗。两种药物在第0小时至90 - 120分钟期间,用力肺活量(FVC)、呼气峰值流速(PEFR)均有统计学意义的改善。维拉帕米治疗时呼吸频率、脉搏率、血压变化不显著,而硝苯地平治疗时出现明显的心动过速和血压短暂下降。

相似文献

1
Effect of aerosolised verapamil and nifedipine in bronchial asthma.雾化维拉帕米和硝苯地平对支气管哮喘的影响。
J Assoc Physicians India. 1993 Jul;41(7):425-7.
2
Calcium channel blockers and terbutaline--a positive interaction.钙通道阻滞剂与特布他林——一种积极的相互作用。
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[Use of calcium antagonists in therapy of bronchial asthma].
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[Evaluation of the protective effects of nifedipine and verapamil in patients with bronchial hyperreactivity].
Wiad Lek. 1989 Feb 1;42(3):129-33.
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Effect of verapamil on allergen-induced asthma in patients with respiratory allergy.维拉帕米对呼吸道过敏患者变应原诱导性哮喘的影响。
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Use of inhaled calcium channel blocking agents in the treatment of asthma.吸入性钙通道阻滞剂在哮喘治疗中的应用。
J Asthma. 1984;21(6):443-50. doi: 10.3109/02770908409083225.
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[Comparative studies of the effects of nifedipine, verapamil and diltiazem on respiratory mechanics in patients with atopic and non-atopic asthma].[硝苯地平、维拉帕米和地尔硫䓬对特应性和非特应性哮喘患者呼吸力学影响的比较研究]
Pol Tyg Lek. 1988;43(42-43):1358-60.
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[Effects of nifedipine on pollen-antigen-induced bronchoconstriction in asthmatics].硝苯地平对哮喘患者花粉抗原诱导的支气管收缩的影响
Zhonghua Jie He He Hu Xi Za Zhi. 1989 Jun;12(3):131-4, 190.
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[Effects of the inhalation of verapamil in bronchial asthma].[维拉帕米吸入对支气管哮喘的影响]
Clin Ter. 1985 Oct 31;115(2):91-3.

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Clinical evaluation of nebulized verapamil in out-patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease.雾化维拉帕米治疗慢性阻塞性肺疾病相关性肺动脉高压患者的临床评估。
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