Gupta S, Meena H S, Chopra R, Bidani R
Department of Medicine, Lady Hardinge Medical College, New Delhi.
J Assoc Physicians India. 1993 Jul;41(7):425-7.
Twenty patients of bronchial asthma were given 5 mg of either nifedipine or verapamil as aerosol therapy in a randomized fashion. Both drugs showed a statistically significant improvement in FVC, PEFR at zero hours lasting through 90-120 minutes. Changes in respiratory rate, pulse rate, blood pressure were insignificant with verapamil while appreciable tachycardia and transient fall in BP occurred with nifedipine therapy.
20例支气管哮喘患者被随机给予5毫克硝苯地平或维拉帕米进行雾化治疗。两种药物在第0小时至90 - 120分钟期间,用力肺活量(FVC)、呼气峰值流速(PEFR)均有统计学意义的改善。维拉帕米治疗时呼吸频率、脉搏率、血压变化不显著,而硝苯地平治疗时出现明显的心动过速和血压短暂下降。