Schneider S M, Michelson E A
University of Pittsburgh Medical Center, Department of Emergency Medicine, Montefiore University Hospital, PA 15213.
Vet Hum Toxicol. 1993 Dec;35(6):503-5.
Activated charcoal is often given through small-bore tubing for pediatric patients or in attempts to bypass the stomach in patients who are vomiting. The viscosity makes activated charcoal difficult to administer through small-bore tubing. This in vitro study examined several interventions to facilitate flow of aqueous suspension activated charcoal through the small-bore tubing. Aqueous suspension activated charcoal with or without sorbitol had similar flow rates. Precoating the tubing with mineral oil gave only minimal increases in flow rate. A 10% dilution decreased the time to administer 240 ccs of aqueous suspension activated charcoal by 2/3. An additional 10% dilution reduced the time to administer the same dose a further 50%. Minimal dilution of aqueous suspension activated charcoal with tap water greatly increased flow rate through small-bore tubes.
活性炭通常通过小口径管道给予儿科患者，或者用于试图绕过正在呕吐的患者的胃部。其粘性使得活性炭难以通过小口径管道给药。这项体外研究考察了几种促进水悬浮液活性炭通过小口径管道流动的干预措施。含或不含山梨醇的水悬浮液活性炭具有相似的流速。用矿物油预涂管道只会使流速有极小的增加。10%的稀释使给予240毫升水悬浮液活性炭的时间减少了三分之二。再额外10%的稀释又将给予相同剂量的时间进一步减少了50%。用自来水对水悬浮液活性炭进行最小程度的稀释极大地提高了通过小口径管道的流速。
