Colbert D L, Turner G J, Gooch J C
Department of Chemical Pathology, Medical College of St Bartholomew's Hospital, London, UK.
Ann Clin Biochem. 1993 Nov;30 ( Pt 6):555-8. doi: 10.1177/000456329303000605.
The Abbott TDx is frequently used for therapeutic drug monitoring of phenytoin concentrations, but reagent costs are high. In an attempt to reduce these costs, we investigated the preparation of in-house reagents. A commercial antiserum was available at reasonable cost and the fluorescent tracer was easily prepared. We describe the preparation of these reagents and their application to the TDx system. Substantially reduced costs were obtained using the in-house reagents.
雅培TDx常用于苯妥英浓度的治疗药物监测，但试剂成本很高。为了降低这些成本，我们研究了自制试剂的制备方法。有一种成本合理的市售抗血清，荧光示踪剂也很容易制备。我们描述了这些试剂的制备及其在TDx系统中的应用。使用自制试剂可大幅降低成本。
