Vantrappen G, Ponette E, Geboes K, Bertrand P
Gastroenterology. 1977 Feb;72(2):220-7.
The clinical, radiological, and endoscopic aspects of Yersinia enterocolitica infections in man were studied in a group of 37 adult patients observed in a 4-year period in a single gastrointestinal unit. The diagnosis was based on isolation of the bacterium in all but 1 patient. Abdominal pain and diarrhea were the most prominent symptoms, occurring in 80% of the patients. A syndrome simulating appendicitis was observed in 40%. The duration of symptoms before diagnosis varied from 1 or 2 weeks in 32 patients to several months in 5. On radiological examination the terminal ileum was involved over a distance of 10 to 20 cm in 21 of 24 patients. A coarse, irregular, or nodular mucosal pattern and pictures suggestive of ulcerations were the most prominent and early radiological signs. Endoscopic observations in 13 patients with marked diarrhea showed signs of colitis in 6 and aphthoid ulcers in 2 patients. On pathological examination, ulcerations and a nonspecific acute inflammatory cell infiltrate were observed. Although treatment with tetracycline or chloramphenicol resulted in 4 to 6 weeks in the disappearance of most symptoms and signs, pictures of "follicular ileitis" persisted for several months.
在一个胃肠科单位，对一组37名成年患者进行了为期4年的观察，研究了人类耶尔森氏小肠结肠炎感染的临床、放射学和内镜检查方面的情况。除1名患者外，所有患者的诊断均基于细菌的分离培养。腹痛和腹泻是最突出的症状，80%的患者出现这些症状。40%的患者出现了类似阑尾炎的综合征。诊断前症状持续时间从32名患者的1或2周至5名患者的几个月不等。在放射学检查中，24名患者中有21名患者的回肠末端受累长度为10至20厘米。粗糙、不规则或结节状的黏膜形态以及提示溃疡的影像表现是最突出和早期的放射学征象。对13名腹泻明显的患者进行内镜观察发现，6名患者有结肠炎体征，2名患者有口疮样溃疡。病理检查发现有溃疡和非特异性急性炎症细胞浸润。尽管使用四环素或氯霉素治疗4至6周后大多数症状和体征消失，但“滤泡性回肠炎”的影像表现持续了几个月。
