Kirsten D, Rieger U, Schröder K H, Böhle A, Magnussen H
Zentrum für Pneumologie, Krankenhaus Grosshansdorf.
Clin Investig. 1993 Oct;71(10):787-90. doi: 10.1007/BF00190319.
Immunotherapy using bacille Calmette-Guérin (BCG) has gained increasing acceptance in the management of superficial bladder cancer. Systemic reactions after intravesical instillation of BCG are rare. However, when the therapy is complicated, the lung often becomes involved. Since the pathogenesis of lung infiltrates after immunotherapy is unknown, we report on a patient who developed a lung infiltrate after receiving BCG immunotherapy for bladder cancer. The infectious etiology was established by culture confirmation of a BCG strain in the bronchoalveolar lavage fluid.
使用卡介苗（BCG）进行免疫疗法在浅表性膀胱癌的治疗中越来越被广泛接受。膀胱内灌注BCG后的全身反应很少见。然而，当治疗出现并发症时，肺部常常会受到影响。由于免疫治疗后肺部浸润的发病机制尚不清楚，我们报告了一名在接受BCG免疫治疗膀胱癌后出现肺部浸润的患者。通过支气管肺泡灌洗 fluid中BCG菌株的培养确认确定了感染病因。 （注：最后一句中“fluid”前面似乎少了个“alveolar”，原文可能有误）
