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通过电刺激迷走神经释放血管活性肠肽(VIP)。

Release of vasoactive intestinal polypeptide (VIP) by electric stimulation of the vagal nerves.

作者信息

Schaffalitzky de Muckadell O B, Fahrenkrug J, Holst J J

出版信息

Gastroenterology. 1977 Feb;72(2):373-5.

PMID:830595
Abstract

The concentration of immunoreactive VIP was measured in portal venous and peripheral arterial plasma in anesthetized pigs. Following electric stimulation of the vagal nerves the median concentration of VIP in portal plasma rose from 21 to 58 pmol l-1 and a simultaneous increase was found in arterial plasma. Atropine did not abolish this effect of vagal stimulation. The response is interpreted as increased release of VIP.

摘要

在麻醉猪的门静脉血浆和外周动脉血浆中测量免疫反应性血管活性肠肽(VIP)的浓度。电刺激迷走神经后,门静脉血浆中VIP的中位浓度从21皮摩尔/升升至58皮摩尔/升,同时动脉血浆中也出现了相应增加。阿托品并未消除迷走神经刺激的这一效应。该反应被解释为VIP释放增加。

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