Early hypoperfusion of technetium-99m hexamethylprophylene amine oxime brain single photon emission computed tomography in a patient with carbon monoxide poisoning.

Single photon emission computed tomography (SPECT) with technetium-99m (99mTc) hexamethylprophylene amine oxime (HM-PAO) were repeatedly performed in a 55-year-old woman with carbon monoxide (CO) poisoning. The initial brain SPECT 10 days after anoxic insult showed focal hypoperfusion which appeared 20 days prior to the onset of delayed neurologic sequelae, and the findings of follow-up SPECTs correlated with the clinical course of CO poisoning. The possibilities of early hypoperfusion on SPECT of acute CO poisoning were discussed.