Hofmann C, Schirle S
Fortschr Med. 1993 Dec 20;111(35-36):562-4.
Numerous clinical studies have demonstrated the efficacy of calcipotriol, a synthetic vitamin D3 analogue, in the treatment of mild to moderate chronic psoriasis.
Report on clinical experience of 40 psoriasis patients treated with calcipotriol, alone or in combination with phototherapy.
After four weeks of treatment, the condition had largely cleared up in eleven out of 18 patients (61%) receiving calcipotriol alone, and in 20 out of 22 patients (91%) receiving combination treatment with UVB or UVA plus UVB. The new anti-psoriasis agent was well tolerated and readily accepted by the patients.
Calcipotriol represents a valuable addition to the available therapy spectrum in chronic psoriasis.
大量临床研究已证实，合成维生素D3类似物卡泊三醇在治疗轻至中度慢性银屑病方面具有疗效。
报告40例银屑病患者单独使用卡泊三醇或联合光疗的临床经验。
治疗四周后，18例单独接受卡泊三醇治疗的患者中有11例（61%）病情基本消退，22例接受UVB或UVA加UVB联合治疗的患者中有20例（91%）病情基本消退。这种新型抗银屑病药物耐受性良好，患者易于接受。
卡泊三醇是慢性银屑病现有治疗方法中的一种有价值的补充药物。
