Health Bull (Edinb). 1993 Nov;51(6):418-29.
In 1987 it became apparent that the number of drug injectors with HIV infection living in a district in the north of Glasgow was increasing. As this area was well served by a wide variety of clinical, epidemiological and laboratory facilities, a multidisciplinary group was convened to examine the extent and spread of infection, and its relationship to behavioural and environmental factors. By 1989 a World Health Organisation working group had developed a standardised methodology, consisting of an interview schedule and voluntary anonymous HIV testing procedures. The study has been implemented annually in Glasgow since 1990, with a collateral project evaluating prevalence of injecting drug use in the general population. The Glasgow HIV Behavioural and Prevalence Study was designed to yield as representative as possible a sample of the city's injectors, respondents being drawn from a variety of in-treatment and out-of-treatment sites. Of the estimated 8,500 injectors in Glasgow (1.35% of the population aged 15-55), 503 and 535 injectors were recruited to the study in 1990 and 1991 respectively. Over 90% of respondents injected daily and reported injecting, on average, four different types of drugs in the six months prior to interview, the three most commonly injected drugs being buprenorphine, heroin and temazepam. There is evidence of HIV risk reduction for sharing of injecting equipment and for using condoms with casual sexual partners. Salivary testing has proved to be successful, less than 5% of respondents refusing to be tested; the prevalence rate was 1.8% in 1990 and 1.1% in 1991. While HIV prevalence remains low, all-cause mortality among injectors in Glasgow is high; drug injecting is probably responsible for more deaths among people aged under 40 than any other factor. At the present time, the drug injecting epidemic in Glasgow poses a considerable challenge to the city's public health services.
1987年,有明显迹象表明,居住在格拉斯哥北部某区感染艾滋病毒的药物注射者人数正在增加。由于该地区拥有各种各样的临床、流行病学和实验室设施,于是召集了一个多学科小组来调查感染的范围和传播情况,以及它与行为和环境因素的关系。到1989年,世界卫生组织的一个工作组制定了一种标准化方法,包括一份访谈时间表和自愿匿名艾滋病毒检测程序。自1990年以来,这项研究每年在格拉斯哥实施,同时还有一个并行项目评估普通人群中注射吸毒的流行情况。格拉斯哥艾滋病毒行为与流行率研究旨在尽可能获取该市注射者的代表性样本,受访者来自各种接受治疗和未接受治疗的场所。据估计,格拉斯哥有8500名注射者(占15至55岁人口的1.35%),1990年和1991年分别有503名和535名注射者被招募到该研究中。超过90%的受访者每天注射,并报告在访谈前六个月平均注射四种不同类型的药物,最常注射的三种药物是丁丙诺啡、海洛因和替马西泮。有证据表明,共用注射设备以及与临时性伴侣使用避孕套可降低感染艾滋病毒的风险。唾液检测已被证明是成功的,拒绝检测的受访者不到5%;1990年的流行率为1.8%,1991年为1.1%。虽然艾滋病毒流行率仍然很低,但格拉斯哥注射者的全因死亡率很高;药物注射可能导致40岁以下人群死亡的人数比任何其他因素都多。目前,格拉斯哥的药物注射流行对该市的公共卫生服务构成了相当大的挑战。