哺乳动物细胞生殖死亡模型。I. 基本假设和一般方程。
Model of mammalian cell reproductive death. I. Basic assumptions and general equations.
作者信息
Obaturov G M, Moiseenko V V, Filimonov A S
机构信息
Medical Radiological Research Centre, Russian Medical Science Academy, Obninsk.
出版信息
Radiat Environ Biophys. 1993;32(4):285-94. doi: 10.1007/BF01225916.
A systemic model describing the major radiobiological effects of various types of radiation is proposed. The model base lines were substantiated, and general mathematical equations for cell survival developed. The model takes into consideration such physical and biological factors as linear energy transfer, ion track structure, and structural and functional organization of interphase chromatin. This paper presents the basic assumptions made and general equations for the cell killing.
提出了一个描述各类辐射主要放射生物学效应的系统模型。该模型的基线得到了证实，并推导了细胞存活的一般数学方程。该模型考虑了诸如传能线密度、离子径迹结构以及间期染色质的结构和功能组织等物理和生物学因素。本文介绍了所作的基本假设以及细胞杀伤的一般方程。
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