对与单核吞噬细胞系统细胞发生反应的临时车间集群的研究。
An investigation of temporary workshop clusters reacting with cells of the mononuclear phagocytic system.
作者信息
Hall G A, Sopp P, Howard C J
机构信息
AFRC Institute for Animal Health, Compton, Newbury, UK.
出版信息
Vet Immunol Immunopathol. 1993 Nov;39(1-3):225-36. doi: 10.1016/0165-2427(93)90185-7.
Monoclonal antibodies (mAbs) within ten temporary workshop clusters (TC3, TC8, TC9, TC11, TC16, TC17, TC19, TC20, TC21 and TC31) which from preliminary evidence appeared to recognize molecules expressed by cells of the mononuclear phagocytic system were studied by immunohistology and flow cytometry. A number of mAbs were identified that were potentially useful for immunohistological studies of the mononuclear phagocytic system. The results confirmed the specificity of a number of CD11a, CD11b, CD11c and CD44 mAbs. The findings also indicated that for several TCs the mAbs could not be regarded as recognizing the same molecule.
对十个临时工作坊集群（TC3、TC8、TC9、TC11、TC16、TC17、TC19、TC20、TC21和TC31）中的单克隆抗体（mAb）进行了研究，初步证据显示这些抗体似乎能识别单核吞噬系统细胞表达的分子，研究方法为免疫组织学和流式细胞术。鉴定出了一些对单核吞噬系统免疫组织学研究可能有用的单克隆抗体。结果证实了多种CD11a、CD11b、CD11c和CD44单克隆抗体的特异性。研究结果还表明，对于几个工作坊集群而言，这些单克隆抗体不能被视为识别同一分子。
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