Jiang J J, Titze I R, Wexler D B, Gray S D
Dept of Speech Pathology and Audiology, University of Iowa, Iowa City 52242.
Ann Otol Rhinol Laryngol. 1994 Feb;103(2):145-8. doi: 10.1177/000348949410300211.
A submucosal fat autograft was implanted within the cover of injured vocal folds of 5 dogs. The implant occurred 6 weeks after unilateral mucosal excision had been performed. Three months postoperatively the larynges of these animals were excised and their phonation was compared to that of normal dog larynges and to other larynges with mucosal excision (but without fat grafting). Radiated acoustic pressure from the artificially driven larynges was recorded and digitized at 20 kHz with 16-bit resolution. Amplitude and fundamental frequency perturbations were extracted from a segment of phonation to assess the stability of the acoustic signals from the 3 groups. It was found that fat augmentation after mucosal excision reduced amplitude and frequency perturbation measures. There was no significant difference between fat-augmented and normal vocal folds. The acoustic measures were also positively correlated with phonation threshold and phonation efficiency measures reported earlier. The results suggest that submucosal fat autograft implantation within an injured vocal fold cover can restore not only the "ease" of phonation, but also the stability of phonation, which is a component of vocal quality.
将自体黏膜下脂肪移植到5只犬受伤声带的被覆层内。移植在单侧黏膜切除术后6周进行。术后3个月切除这些动物的喉部，并将它们的发声与正常犬喉部以及其他行黏膜切除（但未进行脂肪移植）的喉部进行比较。对人工驱动喉部发出的辐射声压进行记录，并以20kHz、16位分辨率进行数字化处理。从一段发声中提取幅度和基频微扰，以评估三组声学信号的稳定性。结果发现，黏膜切除后脂肪填充可降低幅度和频率微扰指标。脂肪填充的声带与正常声带之间无显著差异。这些声学指标也与先前报道的发声阈值和发声效率指标呈正相关。结果表明，在受伤声带被覆层内植入自体黏膜下脂肪不仅可以恢复发声的“轻松程度”，还能恢复发声的稳定性，而发声稳定性是嗓音质量的一个组成部分。
