Crow T, Pengidore T
Department of Neurobiology and Anatomy, University of Texas Medical School, Houston 77225.
Brain Res. 1993 Nov 19;628(1-2):305-8. doi: 10.1016/0006-8993(93)90969-t.
Serotonin (5-HT) produces both short- and long-term enhancement of generator potentials in identified type B-photoreceptors of Hermissenda. The actions of 5-HT have been shown to modulate both light- and voltage-dependent conductances. To further examine light-dependent processes we studied spontaneous and light-elicited discrete waves in the presence of 5-HT. Serotonin significantly increased the frequency of light-elicited discrete waves without initially increasing spontaneous discrete waves recorded in the dark. The increase in discrete wave frequency produced by 5-HT could not be described by a simple Poisson process, since the observed interval distribution after 5-HT application deviated significantly from the predicted exponential interval distribution.
血清素（5-羟色胺，5-HT）可使海兔（Hermissenda）中已识别的B型光感受器的发生器电位产生短期和长期增强。5-HT的作用已被证明可调节光依赖性和电压依赖性电导。为了进一步研究光依赖性过程，我们在5-HT存在的情况下研究了自发的和光诱发的离散波。血清素显著增加了光诱发离散波的频率，而最初并未增加在黑暗中记录的自发离散波。5-HT产生的离散波频率增加不能用简单的泊松过程来描述，因为在应用5-HT后观察到的间隔分布与预测的指数间隔分布有显著偏差。
