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[长沙中风危险因素干预试验的模型与结果]

[The model and results of intervention trial of stroke risk factors in Changsha].

作者信息

Yang Q D

机构信息

Department of Neurology, Xiangya Hospital, Hunan Medical University, Changsha.

出版信息

Zhonghua Yi Xue Za Zhi. 1993 Oct;73(10):612-4, 638-9.

PMID:8313185
Abstract

To develop an effective method for minimizing the incidence and mortality of cerebrovascular disease, we studied the sample population of intervention community (8,052 subjects) and control community (8,065 subjects) in Changsha. 2,631 subjects in the intervention community and 2,733 subjects in the control community with age more than 35 years were enrolled for a cohort study from January 1, 1986 to December 31, 1990. The annual incidence of stroke was 315/10(5) in the control community and 220/10(5) in the intervention community. The annual incidence of stroke was significantly lower in the intervention community than in the control community (P < 0.01). The incidence of stroke in 1990 dropped by 66.4% compared to that in 1986 in the intervention community. But, in the control community it dropped by 9.7%. The change of the mortality and incidence of stroke in the two communities was similar.

摘要

为了开发一种有效方法以降低脑血管疾病的发病率和死亡率,我们对长沙干预社区(8052名受试者)和对照社区(8065名受试者)的样本群体进行了研究。1986年1月1日至1990年12月31日,干预社区2631名年龄超过35岁的受试者和对照社区2733名年龄超过35岁的受试者被纳入队列研究。对照社区中风的年发病率为315/10⁵,干预社区为220/10⁵。干预社区中风的年发病率显著低于对照社区(P<0.01)。干预社区1990年中风发病率与1986年相比下降了66.4%。但是,对照社区下降了9.7%。两个社区中风死亡率和发病率的变化相似。

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