Levison M E, Corman L C, Carrington E R, Kaye D
Am J Obstet Gynecol. 1977 Jan 1;127(1):80-5. doi: 10.1016/0002-9378(77)90318-0.
This study enumerated the predominant vaginal flora in 25 healthy patients: 18 prenatal (six with and 12 without gonorrhea) and seven nonpregnant without gonorrhea. All 25 patients had aerobes and 19 of the 25 had anerobes isolated in titers of greater than or equal to 10(5) colony-forming units (CFU per milliliter). The most frequently isolated microorganism was the lactobacillus (aerobic and anaerobic species) followed by C. vaginale, viridans streptococci, anaerobic gram-positive cocci, and Bifidobacterium sp. Bacteroides fragilis was not isolated. There were no significant differences in the frequency of isolation of any specific microorganism or bacterial counts between pregnant and nonpregnant women or between pregnant women with and without gonorrhea (p greater than 0.05), except pregnant patients had significantly higher total facultative counts associated with significantly lower anaerobic lactobacilli counts and higher C. vaginale counts (p less than 0.01) than in nonpregnant patients.
本研究对25名健康患者的主要阴道菌群进行了计数：18名产前患者（6名患有淋病，12名未患淋病）和7名未患淋病的非孕妇。所有25名患者均有需氧菌，25名中有19名分离出厌氧菌，其滴度大于或等于10(5) 菌落形成单位（每毫升CFU）。最常分离出的微生物是乳酸杆菌（需氧和厌氧种类），其次是阴道加德纳菌、草绿色链球菌、厌氧革兰氏阳性球菌和双歧杆菌属。未分离出脆弱拟杆菌。在任何特定微生物的分离频率或细菌计数方面，孕妇与非孕妇之间或患有淋病与未患淋病的孕妇之间均无显著差异（p>0.05），但与非孕妇相比，孕妇的总兼性菌计数显著更高，同时厌氧乳酸杆菌计数显著更低，阴道加德纳菌计数更高（p<0.01）。
