Charbonneau Mark R, Blanton Laura V, DiGiulio Daniel B, Relman David A, Lebrilla Carlito B, Mills David A, Gordon Jeffrey I
Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Nature. 2016 Jul 7;535(7610):48-55. doi: 10.1038/nature18845.
When most people think of human development, they tend to consider only human cells and organs. Yet there is another facet that involves human-associated microbial communities. A microbial perspective of human development provides opportunities to refine our definitions of healthy prenatal and postnatal growth and to develop innovative strategies for disease prevention and treatment. Given the dramatic changes in lifestyles and disease patterns that are occurring with globalization, we issue a call for the establishment of 'human microbial observatories' designed to examine microbial community development in birth cohorts representing populations with diverse anthropological characteristics, including those undergoing rapid change.
当大多数人想到人类发展时，他们往往只考虑人类细胞和器官。然而，还有另一个方面涉及与人类相关的微生物群落。从微生物角度看待人类发展，为完善我们对健康产前和产后生长的定义以及制定疾病预防和治疗的创新策略提供了机会。鉴于全球化进程中生活方式和疾病模式正在发生巨大变化，我们呼吁建立“人类微生物观测站”，旨在研究代表具有不同人类学特征人群（包括那些经历快速变化的人群）的出生队列中的微生物群落发展情况。
