Radford A
Department of Genetics, University of Leeds, UK.
J Mol Evol. 1993 Apr;36(4):389-95. doi: 10.1007/BF00182186.
Orotidine 5'-monophosphate decarboxylase protein sequences from 14 fungi, 1 slime mold, 2 mammals, and 3 bacteria are compared and aligned and shown to be homologous. Based on the optimal alignment of the fungal sequences, a phylogenetic tree is derived. Within the fungi, the fission yeast Schizosaccharomyces pombe shows a closer relationship to both basidiomycetes and phycomycetes than it does to orthodox ascomycetes (plectomycetes, pyrenomycetes, and budding yeasts). Intron conservation shows a close relationship between phycomycetes and basidiomycetes. The imperfect fungi Trichoderma and Cephalosporium are shown to be closely related to Neurospora. The predicted origin of the group of budding yeasts is dependent on the analytical method used.
对来自14种真菌、1种黏菌、2种哺乳动物和3种细菌的乳清苷5'-单磷酸脱羧酶蛋白质序列进行了比较和比对,结果显示它们具有同源性。基于真菌序列的最佳比对,构建了系统发育树。在真菌内部,裂殖酵母粟酒裂殖酵母与担子菌和藻状菌的关系比与正统子囊菌(盘菌、核菌和出芽酵母)的关系更为密切。内含子保守性表明藻状菌和担子菌之间存在密切关系。不完全真菌木霉属和头孢霉属被证明与脉孢菌密切相关。出芽酵母群的预测起源取决于所使用的分析方法。