Güldal M, Karaoguz R, Akalin H, Bayar M, Akyol T
Department of Cardiology, Ankara University, School of Medicine, Turkey.
Jpn Heart J. 1993 Mar;34(2):221-6. doi: 10.1536/ihj.34.221.
The interaction between amiodarone and the defibrillation threshold (DFT) is still controversial. We present a case with dilated cardiomyopathy and recurrent sustained monomorphic ventricular tachycardia who received an automatic implantable cardioverter defibrillator (AICD) while under long-term amiodarone treatment. AICD implantation was performed without thoracotomy. The transvenous lead was inserted via a left subclavian vein puncture and the patch was placed on the lateral chest wall, submuscularly. At the time of implantation a 35J shock was not successful in converting ventricular fibrillation to sinus rhythm, but a 40J rescue shock was successful. After discontinuation of amiodarone, DFT measurements were repeated. Sixteen days later DFT was still higher than 34J, but 71 days later it decreased to 20J.
胺碘酮与除颤阈值（DFT）之间的相互作用仍存在争议。我们报告一例扩张型心肌病合并复发性持续性单形性室性心动过速患者，该患者在长期胺碘酮治疗期间接受了植入式心律转复除颤器（AICD）。AICD植入术未行开胸手术。经静脉导线通过左锁骨下静脉穿刺插入，补片置于胸壁外侧肌肉下。植入时，35J电击未能将室颤转为窦性心律，但40J抢救电击成功。停用胺碘酮后，重复进行DFT测量。16天后DFT仍高于34J，但71天后降至20J。
